Dr SANKARGANESH ARUNACHALAM
MSc, PhD
ASSOCIATE PROFESSOR
MSc, PhD
ASSOCIATE PROFESSOR
Articles in Journals
| Sl.No. | Title | Name of Journal / Vol. No. / Issue No. / Page Nos | ISSN No. | Date Published |
| 1 | The role of ferroptosis in doxorubicin-induced cardiotoxicity ? An update | Life Sciences / / / - | 1879-0631 | 26-Aug-2025 |
| 2 | Elucidating the interplay of PPAR gamma inhibition and energy demand in adriamycin-induced cardiomyopathy: In Vitro and In Vivo perspective | Journal Of Biochemical And Molecular Toxicology / 38 / 10 / - | 1095-6670 | 27-Sep-2024 |
| 3 | Adriamycin downregulates the expression of KLF4 in cardiomyocytes in vitro and contributes to impaired cardiac energy metabolism in Adriamycin-induced cardiomyopathy | 3 Biotech / / / - | 2190-572X | 25-Apr-2023 |
| 4 | A Hypothesis Concerning the role of PPAR family on Cardiac Energetics in Adriamycin-Induced Cardiomyopathy | Journal of Applied Toxicology / / / - | 0260-437X | 06-Aug-2022 |
| 5 | Exploring the Pattern of Metabolic Alterations Causing Energy Imbalance via PPARα Dysregulation in Cardiac Muscle During Doxorubicin Treatment | Cardiovascular Toxicology / / / - | 1530-7905 | 14-Feb-2022 |
| 6 | Doxorubicin Disrupts the Calcium Homeostasis through its Antagonistic Activity on PINK1?An In-silico Approach | Biointerface Research in Applied Chemistry / 13 / 1 / 1 - 13 | 2069-5837 | 12-Feb-2022 |
| 7 | Exploring the Role of Melatonin in Meditation on Cardiovascular Health | Biointerface Research in Applied Chemistry / 13 / 1 / 1 - 18 | 2069-5837 | 02-Feb-2022 |
| 8 | Disruption of Glycolysis, TCA Cycle, Respiratory Chain, Calcium and Iron Homeostasis in Doxorubicin Induced Cardiomyopathy-An In-silico Approach | Biointerface Research in Applied Chemistry / / / - | 2069-5837 | 12-Dec-2021 |
| 9 | Pharmacoinformatics-based investigation of bioactive compounds of Rasam (South Indian recipe) against human cancer | Scientific Reports / 11 / 1 / 21488 - | 2045-2322 | 02-Nov-2021 |
| 10 | Mechanisms of doxorubicin-mediated reproductive toxicity-A review | Reproductive Toxicology / / / - | 1873-1708 | 18-Apr-2021 |
| 11 | Adriamycin inhibits glycolysis through downregulation of key enzymes in Saccharomyces cerevisiae | 3 Biotech / 11 / 15 / 1 - 13 | 2190-5738 | 02-Jan-2021 |
| 12 | Removal of water and their soluble materials from fuels using Moringa oleifera loaded keratin-co-sodium acrylate hydrogel | Journal of Porous Materials / 28 / 1 / 515 - 527 | 1380-2224 | 02-Jan-2021 |
| 13 | Targeting complement cascade: an alternative strategy for COVID‑19 | 3 Biotech / 10 / 11 / 1 - 10 | 2190-572X | 19-Oct-2020 |
| 14 | Adipose-Derived Molecules-Untouched Horizons in Alzheimer's Disease Biology | Frontiers in Aging Neuroscience / 12 / 1 / 1 - 12 | 1663-4365 | 13-Feb-2020 |
| 15 | Paeonol Reverses Adriamycin Induced Cardiac Pathological Remodeling through Notch1 Signaling Reactivation in H9c2 Cells and Adult Zebrafish Heart | Chemical Research in Toxicology / 33 / 1 / 312 - 323 | 0893-228X | 16-Jul-2019 |
| 16 | Urinary volatile metabolomics as a viable alternative diagnostic tool for polycystic ovary syndrome: An exploratory hypothesis | Medical Hypotheses / 124 / 1 / 121 - 124 | 0306-9877 | 19-Feb-2019 |
| 17 | Molecular mechanism of doxorubicin-induced cardiomyopathy-An update | European Journal of Pharmacology / 818 / 1 / 241 - 253 | 0014-2999 | 20-Oct-2017 |
| 18 | Adriamycin-induced cardiomyopathy can serve as a model for diabetic cardiomyopathy - a hypothesis | Asian Pacific Journal of Tropical Biomedicine / 7 / 11 / 1041 - 1045 | 2221-1691 | 06-Oct-2017 |
| 19 | Emu oil decreases atherogenic plaque formation in cafeteria diet-induced obese rats | Journal of the Science of Food and Agriculture / 96 / 9 / 3063 - 3068 | 0022-5142 | 29-Sep-2015 |
| 20 | Antioxidant mediated ameliorative steroidogenesis by Commelina benghalensis L. and Cissus quadrangularis L. against quinalphos induced male reproductive toxicity | Pesticide Biochemistry and Physiology / 109 / 1 / 18 - 33 | 0048-3575 | 23-Jan-2014 |
| 21 | Biogenesis of Gold Nanoparticles Using Plant Powders and Assessment of In Vitro Cytotoxicity in 3T3-L1 Cell Line | Journal of Pharmaceutical Innovation / 8 / 1 / 265 - 275 | 1872-5120 | 07-Nov-2013 |
| 22 | Antimicrobial activity of Leucas aspera engineered silver nanoparticles against Aeromonas hydrophila in infected Catla catla | Colloids and Surfaces B: Biointerfaces / 109 / 1 / 20 - 24 | 0927-7765 | 20-Mar-2013 |
| 23 | In vivo antitumor activity of biosynthesized silver nanoparticles using Ficus religiosa as a nanofactory in DAL induced mice model | Colloids and Surfaces B: Biointerfaces / 108 / 1 / 185 - 190 | 0927-7765 | 13-Mar-2013 |
| 24 | Doxorubicin treatment inhibits PPAR gamma and may induce lipotoxicity by mimicking a type 2 diabetes-like condition in rodent models | FEBS Letters / 587 / 1 / 105 - 110 | 0014-5793 | 07-Dec-2012 |
| 25 | Adriamycin inhibits adipogenesis through the modulation of PPAR gamma and restoration of adriamycin-mediated inhibition of adipogenesis by PPAR gamma over-expression | Toxicology Mechanisms and Methods / 22 / 7 / 540 - 546 | 1537-6516 | 12-Apr-2012 |
| 26 | Adriamycin induced spermatogenesis defect is due to the reduction in epididymal adipose tissue mass: A possible hypothesis | Medical Hypotheses / 78 / 1 / 218 - 220 | 0306-9877 | 13-Oct-2011 |
| 27 | Davallialactone protects against adriamycin-induced cardiotoxicity in vitro and in vivo | Journal of Natural Medicines / 66 / 1 / 149 - 157 | 1340-3443 | 21-Aug-2011 |
| 28 | c-myb stimulates cell growth by regulation of insulin-like growth factor (IGF) and IGF-binding protein-3 in K562 leukemia cells | Biochemical and Biophysical Research Communications / 385 / 1 / 38 - 43 | 0006-291X | 08-May-2009 |
Participation in Seminars/Conferences/Symposium
| Sl.No. | Name of the Conference /Seminar /Symposium | Type of Program | Title of the Article | Role | Venue/Place | Date |
| 1 | Hands on Training: Artificial microRNA in Plants | Seminar | Participant) | Kalasalingam Academy of Research and Education | 23/05/2024 | |
| 2 | EUROTOX Faculty Webinar on (Drug-induced) liver toxicity: types and mechanisms | Seminar | Participant) | European Toxicology SocietyWebinar | 30/04/2024 | |
| 3 | SAINTS | Conference | Moderator/Chair) | Christ UniversityCHRIST University | 21/03/2024 | |
| 4 | Advancements of 3R's in Biomedical Research, Laboratory Animal Science and Welfare: International Perspectives | Conference | Participant) | Laboratory Animal Scientists' Association, IndiaBengaluru | 07/11/2023 | |
| 5 | Global Trends in Sustainable Technology and its Applications in Applied Sciences | Conference | Participant) | Reva University, BengaluruBengaluru | 30/10/2023 |
MPhil/PhD Guided/Adjudicated
| Sl.No. | Title | Name of Student | Institution | Role | Status | Month Year |
| 1 | DETERMINATION OF TIME SINCE DEATH BY QUANTIFICATION AND DEGRADATION OF PROTEINS | GREESHMA RAJEEV M | Christ University | Supervisor | Ongoing | March 2024 |
| 2 | ANALYSIS OF POISONED CASES TO DETERMINE THE NATURE OF POISON AND TO PROPOSE A FRAMEWORK FOR RAPID TEST | ZUBIN PHILIP | Christ University | Supervisor | Ongoing | August 2024 |
| 3 | IMPAIRMENT OF CELLULAR LOCOMOTION DUE TO DISRUPTION OF AMINO ACID-,NUCLEIC ACID- METABOLISM AND BIOENERGETICS BY ADRIAMYCIN | PADMINI T H | Christ University | Supervisor | Ongoing | March 2025 |
| 4 | . | POORVI UJJAINIA | Christ University | Supervisor | Ongoing | July 2025 |
| 5 | . | CHRISTINA MARIA M | Christ University | Supervisor | Ongoing | July 2025 |
Research Project
| Sl.No. | Name of the Research Project | Investigator(s) | Sponsors | Internal/External |
| 1 | Elucidation of mechanism of Adriamycin mediated male reproductive toxicity and recovery by restoration of epididymal adipose tissue | SANKARGANESH ARUNACHALAM | Science and Engineering Research Board | External |
| 2 | Elucidating the role of PPAR alpha in the development of doxorubicin-induced cardiomyopathy | SANKARGANESH ARUNACHALAM | Science and Engineering Research Board | External |
| 3 | Unravelling the physiological mechanism of Heartfulness meditation (Pranahuti) - mediated benefits on cardiovascular risk | SANKARGANESH ARUNACHALAM | Department of Science and Technology | External |
| 4 | Evaluation of the effect of Adriamycin on cell cycle using Saccharomyces cerevasiae | SANKARGANESH ARUNACHALAM | Internal |
Workshop/FDP/Training programme
| Sl.No. | Name of the Workshop/FDP/Training programme | Name of Organiser | Level | Role | Date |
| 1 | Academic Enablers of Entrepreneurship: Bridging Ideas, Ecosystems and Incubation | CHRIST Incubation Center, | Institutional | Participant | 28/10/2025 |
| 2 | Advancement in Life Sciences Research | Department of Life Sciences, CHRIST University, | Participant | 29/09/2025 | |
| 3 | DECODING THE BIOPHARMA INDUSTRY: TRENDS, INSIGHTS AND INNOVATIONS | Biozeen Technologies Pvt. Ltd., Bengaluru, Biozeen Technologies Pvt. Ltd., Bengaluru | National | Participant | 07/07/2025 |
| 4 | FDP 2025 | CHRIST, | Institutional | Participant | 19/05/2025 |
| 5 | Learner-Centered Andragogy | CHRIST University, | Participant | 24/03/2025 | |
| 6 | Advancements of 3R's in Biomedical Research, Laboratory Animal Science and Welfare: International Perspectives | Laboratory Animal Scientists' Association, India, Indian Institute of Science | International | Participant | 06/11/2023 |
| 7 | Faculty Orientation Program | CHRIST (Deemed to be University), | Institutional | Participant | 19/09/2023 |
| 8 | Workshop Series on Enhancing Mentoring Skills | CHRIST University, | Regional | Participant | 16/08/2023 |